Automated Heparin-Delivery System to Control Activated Partial Thromboplastin Time
نویسندگان
چکیده
منابع مشابه
Automated heparin-delivery system to control activated partial thromboplastin time: evaluation in normal volunteers.
BACKGROUND Unfractionated heparin is used widely; however, control of the level of anticoagulation remains its greatest problem, with fewer than 35% of patients having activated partial thromboplastin times (aPTTs) within a range of 55 to 85 seconds in recent trials. METHODS AND RESULTS We developed and tested a prototype of an automated heparin control system (AutoHep) in which a computer-ba...
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The pathological activated partial thromboplastin time test is a data that we can find in all clinical laboratories routinely. The hemato-coagulative clinical case here reported aims to point out how the laboratory can provide a correct diagnosis by methodological rational setting and, consequently, carry out an appropriate therapy, or reassure the patient that the pathological data will not ca...
متن کاملUse of the activated partial thromboplastin time in the control of heparin administration.
H EPARIN, which acts as a direct anticoagulant, in contrast to indirect anticoagulants such as the coumarins or indandiones, has been thought by some investigators to fulfill more nearly the role of tile ideal anticoagulant (1-3). This naturally occurring mucopolysaccharide rapidly decreases the activity of the coagulation system by acting both as an antithromboplastin and as an antithrombin. I...
متن کاملBedside heparin monitoring by activated partial thromboplastin time measured with a dry reagent.
Activated partial thromboplastin time (APTT; also coagulation surface induced time [ID is a routine method for monitoring heparin treatment [2-5]. This time is influenced by the type of reagent, the method of analysis, and the laboratory instrument used; thus, the result will vary from one laboratory to another [6, 7]. Variation in heparin sensitivity between batches of re-agents produced from ...
متن کاملAnti-factor Xa and activated partial thromboplastin time measurements for heparin monitoring in mechanical circulatory support.
OBJECTIVES This study investigated the relationship between anti-factor Xa (anti-FXa) and activated partial thromboplastin time (aPTT) for monitoring intravenous unfractionated heparin (IV-UFH) in patients with continuous-flow left ventricular assist devices (CF-LVADs). BACKGROUND CF-LVADs have become mainstream therapy for patients with advanced heart failure. Thromboembolic events, device t...
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ژورنال
عنوان ژورنال: Circulation
سال: 1999
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.99.6.751